DHEA (Dehydroepiandrosterone) is a precursor hormone that plays a crucial role in the production of testosterone in males, estrogen in females, and other types of steroid hormones. It is also involved in the development of male secondary sexual characteristics during puberty.
What Is the Role of DHEA, the Anti-Stress Hormone?
Most DHEA is produced in the adrenal glands, which are two small glands located above the kidneys. These glands help regulate heart rate, blood pressure, and other bodily functions. A small amount of DHEA is also produced in the testes in men and the ovaries in women. If your DHEA levels are abnormal, it could indicate issues with the adrenal glands or reproductive organs (testes or ovaries).
DHEA is a hormone that responds to stress in the body, similar to cortisol. When stress occurs—whether short-term or chronic, physical or psychological—it impacts the brain, including the hypothalamus and pituitary gland, the autonomic nervous system (ANS), and the adrenal glands. This system is known as the HPA axis.
Moreover, DHEA works through various mechanisms to balance and regulate the effects of cortisol. Therefore, DHEA/DHEAS is a vital hormone for the body, significantly influencing metabolism and fat regulation, which in turn affects body weight balance.

The Importance of DHEA
- Supports body growth; serves as a precursor for sex hormone production like testosterone and estrogen.
- Enhances memory and reduces the risk of early-onset dementia.
- Helps regulate mood.
- Increases the body’s ability to cope with stress.
- Strengthens muscles and bones.
- Slows the aging process.
- Boosts the immune system and reduces allergic reactions.
- Aids in weight control.
- Supports brain function.
- Lowers the risk of artery blockage, heart disease, high cholesterol, and reduces the risk of diabetes.
- Helps combat chronic fatigue.
- Enhances metabolism and supports weight management.
Thus, DHEA/DHEAS is a very important hormone for the body, significantly impacting metabolism, fat regulation, and the maintenance of body weight balance.
Laboratory Testing
Hormone tests recommended:
- Cortisol
- DHEA
Note
- No need to fast from food or drink before testing.
- It is recommended to conduct the test between 7:00–10:00 a.m.