(EP2 following EP1: Precision Medicine)
Standing Test: There are many types of genetic code testing programs to suit the conditions and needs of each person.
Hereditary Cancer Genetic Testing
The results will be used to plan personalized cancer screening, and prevention before the disease occurs. They provide increased accuracy of examination.
Common cancer groups such as:
- Breast cancer
- Female reproductive cancers such as ovarian cancer, endometrial cancer.
- Male prostate cancer
- Gastrointestinal cancers such as colorectal cancer, stomach cancer.
- Endocrine system cancers, such as thyroid cancer, endocrine tumours, adrenal tumours, parathyroid glands, pituitary gland.
- Urinary system (kidney, urinary tract prostate.)
- Skin cancer
- Neuro-brain cancer.
- Tissue cell carcinoma.
- Haematology (degenerative bone marrow disease, leukaemia.)
Nutrigenomic Gene Testing – Gene Testing Program for Holistic Health:
Nutrigenomic Gene testing is a specific investigation into nutrition, physical fitness, and immunity at the cellular level by examining genes related to nutrition, both quantitative and individualized, such as those that respond to various nutrients, including adverse reactions from drinking alcohol, caffeine, or drinking lactose-containing milk. It helps evaluate the ability to absorb different vitamins and minerals, as well as testing genes about appetite to guide health care planning.
Choose foods and vitamin supplements that are suitable for the body, with a team of doctors and nutritionists to advise on consumption or supplement each type of food individually.
Each type of food is individual.
| Category | List |
|---|---|
| Diet | - Apprtite - Carbohydrate Sensitivity - Response to polyunsaturated taste reception - Fat taste reception - Salt taste reception - Sweet taste reception |
| Reaction category - Undesirable Food intolerance and sensitivity | - Sodium Sensitivity and Hypertension - Alcohol Flush Reaction - Caffeine Sensitivity - Lactose Intolerance |
| Vitamin and Food Supplements | - Vitamin B12 - Vitamin B6 - Vitamin C - Vitamin A/Beta Carotene - Vitamin D/Calcium - Folate - Omega-3 and DHA - Iron - Vitamin E |
Pharmacogenomics Gene Testing – Pharmacogenomics (PGx)
To assess drug efficacy, severe allergy risk, drug response, and the likelihood of side effects from each drug vary from person to person. This is to reduce the risk of drug allergies and side effects as much as possible.
How important is drug allergy gene testing and drug response?
- To see the risk of drug allergy from genes.
- To check individual drug responses
- To enable doctors to choose effective medications for patients.
- Reduce the chance of side effects from medications
Pharmacogenomics (PGx) assays cover 126 drugs
- Diabetes medications
- Lipid-lowering drugs
- Blood thinners
- Allergy medications
- Painkillers
- Heart disease medicine
- Immune suppressing drugs
- Medicine to treat infection
- Cancer medicine
- Medication to treat gastritis
- Psychiatric drugs
- Sleeping pills
Who is the drug allergy test suitable for?
- Patients with chronic non-communicable diseases such as diabetes, high blood pressure, and hyperlipidaemia. Coronary artery disease, gout, tons.
- Patients with a history of taking multiple medications but find it difficult to control the disease, or having many side effects from medications.
- Patients who need to start taking medications that may cause severe allergic reactions, such as anticonvulsants or uric acid lowering drugs.
- Patients with a history of coronary artery disease who need to take antiplatelet medications to see the precise response to the drug.
- Users of immunosuppressive drugs, antiviral medications, or chronic pain relievers
- Health-conscious people who want to know the results of drug response analysis in order to choose the right medication.
Hereditary Breast and Gynaecologic Cancers Risk Assessment
Breast cancer is the number one most common cancer in Thailand and around the world. The most common and important gynaecological cancers are cervical cancer, uterine cancer, and ovarian cancer, and vulvar cancer.
Hereditary cancer genetic testing is suitable for:
- Cancer patients who need information about whether the cancer is transmitted by blood to their children or siblings.
- A normal person with a family history of cancer and needs more information about whether the disease is transmitted to them.
- Individuals interested in health check-ups and cancer screening.
BRCA1 and BRCA2 gene screening
To assess the risk of breast cancer and hereditary ovarian cancer, namely the BRCA1 and BRCA2 genes.
Exome sequencing for cardiovascular disease.
Accurate and reliable genetic code analysis can help determine the cause of the disease to reduce the risk. Therefore, it is directly beneficial to both the examined person and the kinship family. In healthcare, prevention and treatment of heart disease, severe losses can be reduced. It also increases the chances of living happily and with quality for everyone in the family.
Who is this package suitable for?
A patient or family which has the following history:
- acute heart attack for unknown reasons.
- a relative died of an idiopathic heart disease.
- hyperlipidaemia or premature cardiovascular or brain disease that is suspected to be genetic.
- there is an idiopathic arrhythmia.
- have an aneurysm or tear.
- those who are interested in testing to find out if there is a risk of genetic heart disease.
References
- Precision Medicine in Cancer Treatment. National Cancer Institute. [cancer.gov]
- Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015 Feb 26;372(9):793-5.
- Shotelersuk V, Tongsima S, Pithukpakorn M, Eu-Ahsunthornwattana J, Mahasirimongkol S. Precision medicine in Thailand. Am J Med Genet C Semin Med Genet. 2019 Jun;181(2):245-253.
